The California Highway Patrol reported that at least one person has died in the crash, which took place near Walker Ridge Road, west of the Colusa County line.
The collision was reported at 2:25 p.m., CHP reported.
Officials have shut down the highway, with Caltrans also is on scene to help control traffic.
Updates and a full report will be posted on Lake County News as soon as they are available.
E-mail Elizabeth Larson at This email address is being protected from spambots. You need JavaScript enabled to view it..
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